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mescaline (peyote cactus)

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Buy mescaline online Trimethoxyphenethylamine (also known as mescaline) is a naturally-occurring classical psychedelic substance of the phenethylamine class. It occurs naturally in the peyote cactus (Lophophora williamsii), and a number of other cacti species such as the Echinopsis pachanoi (San Pedro cactus),[3] Echinopsis peruviana (Peruvian Torch) as well as the Cactaceae plant and the Fabaceae bean family. It is one of the oldest known hallucinogens and is the prototypical member of the psychedelic phenethylamines, one of the two major classes of psychedelics (along with tryptamines).

Mescaline was first isolated from peyote in 1897 by the German chemist Arthur Heffter. The ritual use of the peyote cactus has occurred for at least 5700 years by Native Americans in Mexico. Other mescaline-containing cacti such as the San Pedro have a long history of use in the South American continent, spanning from Peru to Ecuador. Mescaline is an important part of the life’s work of the American chemist Alexander Shulgin, who used mescaline as a starting point for synthesizing dozens of novel psychedelic compounds, which he documented in the 1991 book PiHKAL (“Phenethylamines I Have Known and Loved”).

Subjective effects include open and closed-eye visuals, time distortion, enhanced introspection, conceptual thinking, euphoria, and ego loss. It is considered to be one of the most gentle, subtle, and euphoric psychedelics, with a greater emphasis on bodily and tactile sensations (somewhat similar to MDMA) than tryptamines like psilocybin or DMT, which tend to have a more dynamic head-space and visual geometry. Synthetic mescaline is highly sought after and typically produced only in small batches, owing to its low potency and relatively high production cost.

Unlike other highly prohibited substances, mescaline has not been proven to be physiologically toxic or addictive. Nevertheless, adverse psychological reactions such as anxiety, paranoia, delusions and psychosis can still always occur, particularly among those predisposed to mental disorders. It is highly advised to use harm reduction practices if using this substance.

Buy mescaline online

Mescaline, or 3,4,5-trimethoxyphenethylamine, is a substituted phenethylamine featuring a phenyl ring bound to an amino -NH2 group through an ethyl chain. Mescaline contains three methoxy functional groups CH3O- which are attached to carbons R3, R4, and R5 of the phenyl ring. Mescaline acts similarly to other psychedelic agents. It binds to and activates the serotonin 5-HT2A receptor with a high affinity.How activating the 5-HT2A receptor leads to psychedelia is still unknown, but it likely somehow involves excitation of neurons in the prefrontal cortex. Mescaline is also known to bind to and activate the serotonin 5-HT2C receptor.

Mescaline is usually considered to be very energetic and stimulating without being forced. For example, when taken in any environment it will usually encourage physical activities such as running, walking, climbing or dancing. In comparison, other more commonly used psychedelics such as psilocin are generally sedating and relaxed.

The “body high” of mescaline can be described as proportionally intense in comparison to its accompanying visual and cognitive effects. It is manifested in a number of forms including an intense soft, warm glow that grows over the body and is capable of becoming extremely physically euphoric.

This is most similar to MDMA and psilocin and is consistently manifested throughout the experience. This is contrasted by an intensely pleasurable yet sharp, cold electric tingling sensation which moves up and down the body. This is most similar to LSD and is also consistently manifested throughout the experience. The final physical effect noticed throughout the experience is an intense energetic pins and needles sensation that manifests itself in the form of a continuously shifting and tingling sensation that travels up and down the body in spontaneous waves. This is most similar to 2C-B and is not entirely consistent throughout the experience. The visual geometry encountered on mescaline can be described as similar in appearance to that of ayahuasca, 2C-P or psilocin in the sense that its geometry is structured in its organization as well as natural and organic in style. However, in terms of its bright colors, sharp edges and angular corners, it is more similar to that of LSD, 2C-B and 2C-I.

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